[1] SUSPECTED DRE

[A] TOUGH ;B] ANOMALY

[2] INCREASED PSA AGE<50 PSA>2-3ngr/ml

[3] PSA<2.5 ngr/ml

PSA VELOCITY >0.35ngr/ml/YEAR

[4] FAMILY HISTORY

PROSTATE CANCER[382000 IN EUROPE]

BIOPSY[USA][1.000.000/YEAR]

SCREENING INCREASED INCIDENCE OF NOT-SIGNIFICANT VOLUMES